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Indian scientists discover 'genetic switch' inside womb that leads to pregnancy

For a pregnancy to begin, the embryo must first attach and embed itself in the wall of the mother's womb. But how this happens has remained a mystery

Indian scientists discover 'genetic switch' inside womb that leads to pregnancy

Indian scientists discover genetic switch inside womb that leads to pregnancy
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17 Nov 2025 10:08 AM IST

A study by the Indian Council of Medical Research seeking to explain how a pregnancy is initiated has led to the discovery of a "genetic switch" that allows an embryo to implant itself on the wall of the womb, leading to conception.

For a pregnancy to begin, the embryo must first attach and embed itself in the wall of the mother's womb. But how this happens has remained a mystery.

The findings, published in the international journal Cell Death Discovery, revealed a fundamental biological switch that controls embryo implantation. The study was a collaboration between the Indian Council of Medical Research-“National Institute for Research in Reproductive and Child Health (ICMR-NIRRCH), Mumbai; Banaras Hindu University (BHU), Varanasi, and the Indian Institute of Science (IISc), Bengaluru, and brought together experts in molecular biology, genomics and mathematical modelling.

ICMR Study Embryo Implantation Discovery Genetic Switch Reproductive Biology India Scientific Research 
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